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Krum Lab Publications

  1. Lillo MA, Nichols C, Seagroves TN, Miranda-Carboni GA, Krum SA. Bisphenol A Induces Sox2 in ER+ Breast Cancer Stem-Like Cells. Hormones and Cancer. Apr;8(2):90-99, 2017.
  2. Martin A, Yu J, Xiong J, Khalid AB, Katzenellenbogen B, Kim SH, Katzenellenbogen JA, Malaivijitnond S, Gabet Y, Krum SA, Frenkel B. Estrogens and Androgens Inhibit Association of RANKL with the Pre-osteoblast Membrane through Post-translational Mechanisms. J Cell Physiol, 2017.
  3. Maria Angeles Lillo Osuna, Cydney Nichols, Chanel Perry, Stephanie Runke, Raisa Krutilina, Tiffany N. Seagroves, Gustavo A. Miranda-Carboni, Krum SA. Methylparaben stimulates tumor initiating cells in ER+ breast cancer models. Journal of Applied Toxicology. Apr;37(4):417-425,
  4. Morimoto E, Li M, Khalid AB, Krum SA, Chimge NO, Frenkel B. Glucocorticoids Hijack Runx2 to Stimulate Wif1 for Suppression of Osteoblast Growth and Differentiation. J Cell Physiol. Jan;232(1):145-53, 2017
  5. Martin A, Xiong J, Koromila T, Ji JS, Chang S, Song YS, Miller JL, Han CY, Kostenuik P, Krum SA, Chimge NO, Gabet Y, Frenkel B. Estrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association. Feb 17;75:96-104, 2015.
  6. Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. ERα-regulated Lipocalin 2 Expression in Adipose Tissue Links Obesity with Breast Cancer Progression. J Biol Chem. Feb 27;290(9):5566-81, 2015.
  7. Miriam Güemes, Alejandro J. Garcia, Diana Rigueur, Stephanie Runke, Weiguang Wang, Zhao G, Hugo Mayorga, Elisa Atti, Sotirios Tetradis, Bruno Péault, Karen Lyons, Gustavo A. Miranda-Carboni and Krum SA. GATA4 is essential for bone mineralization via ERa and TGFb/BMP pathways. Journal of Bone and Mineral Research, 29, No. 12, pp 2676-2687, 2014.
  8. Korinna Wend, Peter Wend, Brian G. Drew, Andrea L. Hevener, Gustavo A. Miranda-Carboni, and Krum SA. ERa regulates lipid metabolism in bone through ATGL and Perilipin. Journal of Cellular Biochemistry, Jun;114(6):1306-14, 2013.
  9. Peter Wend, Stephanie Runke, Korinna Wend, Brenda Anchondo, Maria Yesayan, Meghan Jardon, Natalie Hardie, Christoph Loddenkemper, Ilya Ulasov, Maciej S. Lesniak, Rebecca Wolsky, Laurent A. Bentolila, Stephen G. Grant, David Elashoof, Stephan Lehr, Jean J. Latimer, Shikha Bose, Husain Sattar, Krum SA and Gustavo A. Miranda-Carboni. WNT10B/β-catenin Signaling Induces HMGA2 and Proliferation in Metastatic Triple-Negative Breast Cancer. EMBO Mol Med. Feb;5(2):264-79, 2013.
  10. Alejandro J. Garcia, Colton Tom, Miriam Guemes, Gloria Polanco, Maria E. Mayorga, Korinna Wend, Gustavo A. Miranda-Carboni, and Krum SA. ERα Signaling Regulates MMP3 Expression to Induce FasL Cleavage and Osteoclast Apoptosis. Journal of Bone and Mineral Research, Vol. 28, No. 2, February 2013, pp 283–290, 2013.
  11. Gustavo A. Miranda-Carboni, Miriam Guemes, Shannon Bailey, Edgar Anaya, Mirko Corselli, Bruno Peault and Krum SA. GATA4 regulates Estrogen Receptor-alpha-Mediated Osteoblast Transcription. Molecular Endocrinology Jul;25(7):1126-36, 2011.
  12. Krum SA, Esther de la Rosa Dalugdugan, Gustavo A. Miranda-Carboni and Timothy F Lane. BRCA1 forms a functional complex with g-H2AX as a late response to genotoxic stress. Journal of Nucleic Acids, Volume 2010, Article ID 801594, 2010.
  13. Lupien M, Eeckhoute J, Meyer CA, Krum SA, Rhodes DR, Liu XS, and Brown M. Coactivator Function Defines the Active Estrogen Receptor-1 α Cistrome. Molecular and Cellular Biology, 29: 3413–3423, 2009.
  14. Miranda-Carboni GA., Krum SA, Yee K, Nava M, Deng QE, Pervin S, Collado-Hidalgo A, Galić Z, Zack JA, Nakayama K, Nakayama KI, Lane TF. A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors. Genes and Development, 22: 3121-3134, 2008.
  1. Krum SA, Miranda-Carboni GA, Lupien M, Eeckhoute J, Carroll JS, and Brown M. Unique ER{alpha} cistromes control cell type-specific gene regulation. Molecular Endocrinology, 22 (11): 2393-2406, 2008.
  2. Krum SA, Miranda-Carboni GA, Hauschka PV, Carroll JS, Lane TF, Freedman LP and Brown M. Estrogen Protects Bone by Inducing Fas Ligand in Osteoblasts to Regulate Osteoclast Survival. The EMBO Journal. 27: 535–545, 2008.
  3. Eeckhoute J, Keeton EK, Lupien M, Krum SA, Carroll JS and Brown M. A positive cross-regulatory loop ties GATA-3 to estrogen receptor a expression in breast cancer. Cancer Research. 67:6477-83, 2007.
  1. Krum SA, Miranda GA, Lin C, Lane TF. BRCA1 associates with processive RNA polymerase II. Journal of Biological Chemistry. 278: 52012-52020, 2003.
  2. Krum SA, Womack JE, and Lane TF. Bovine BRCA1 shows classic responses to genotoxic stress but low in vitro transcriptional activation activity. Oncogene. 22: 6032-6044, 2003.

Peer-reviewed Reviews

  1. Khalid AB and Krum SA. Estrogen receptors alpha and beta in bone. Bone. 2016 Apr 9;87:130-135.
  2. Korinna Wend, Peter Wend and Krum SA. Tissue Specific Effects of Loss of Estrogen During Menopause and Aging. Frontiers in Endocrinology of Aging 3:19, 2012.
  3. Peter Wend, Korinna Wend, Krum SA, Gustavo A. Miranda-Carboni. The role of WNT10B in physiology and disease. Acta Physiologica, 2011.
  4. Krum SA. Direct Transcriptional Targets of Sex Steroid Hormones in Bone. Journal of Cellular Biochemistry. 112:401–408, 2011.
  5. Krum SA, Jia Chang, Gustavo Miranda-Carboni & Cun-Yu Wang. Novel functions for NFκB: inhibition of bone formation. Nature Reviews Rheumatology. Oct;6(10):607-11, 2010.
  6. Krum SA and Brown M. Unraveling Estrogen Action in Osteoporosis. Cell Cycle. 7: 1348-1352, 2008.